This quote is saying that art can be both broad and detailed. It means that art involves looking at the overall ‘big picture’ of something – looking at the larger and more obvious elements of a piece. But an artist can also look at the smaller, more mundane details. They can look closer and examine the little things to create something special. The quote is suggesting that this closer examination of the seemingly unimportant can be an important part of art, and that it is possible to “see the whole world in a grain of sand” – that is to say, to see the great and wondrous in the small and seemingly insignificant.