Everyone wants clean air and clean water, but my hope is that we will not regulate it to the point where we drive businesses and industries out of this country, to the point where entrepreneurs cannot start or expand their businesses because they simply can't afford to do so.

This quote is saying that people want clean air and water but the speaker hopes that it won’t be regulated too strictly. Regulations can be costly and if they become too expensive, it could end up causing businesses and industries to leave the country. This could make it harder for people to start or improve their businesses since they would not be able to afford the regulations.