I like doing comedy, I like doing drama. Naturally I like to do, I like doing dramas, I like conflict, and when I do a comedy, you know, I've found that, like, romantic comedy is the trickiest one, because often it's neither: it's not romantic and it's not funny. So, like, I like a comedy that's biting. It's biting humor or really quirky humor.

This quote is about how the speaker prefers to do comedy and drama as an actor. They find romantic comedies to be the most challenging, as they often fail to make the audience feel either love or laughter. The speaker prefers comedies that are “biting,” in other words they make the audience think while they laugh, or those with “quirky humor,” which is humorous in a strange, offbeat way.