This quote is referring to the comedic style of Larry David, a famous comedian, actor, and writer. The speaker is suggesting that a central part of Jewish history has been a comedic style of self-deprecation and self-criticism. This style is exemplified by the popular writing and commentary of the Talmud, an ancient rabbinical text, and can be seen in much of modern Jewish comedy. The speaker is implying that they see the same kind of self-critique in the comedic style of Larry David and can appreciate it because of its historical roots.