In life, you can blame a lot of people and you can wallow in self-pity, or you can pick yourself up and say, 'Listen, I have to be responsible for myself.'

This quote means that when something bad happens in life, you have two choices: you can either blame other people and feel sorry for yourself, or you can take responsibility for what happened and decide to make things better. Taking responsibility for yourself means that you don’t wait for someone else to make things right for you, but instead you take the initiative to make things better.