This quote is saying that people feel both uncertain and pessimistic about the current situation, but still hoping for something better in the future. Insecurity is being unsure of something or feeling anxious, while resignation is the feeling of helplessness or acceptance of something. Hope is feeling confident about the future or wishing for something to happen. When these three feelings are combined together, it can be interpreted as people feeling unsure and pessimistic about their current circumstances and still believing that the future can be different and better.