I've learned from my dealings with Johnny Carson that no matter what kind of friendship you think you have with people you're working with, when the chips are down, it's all about business.

This quote is a lesson that Johnny Carson taught someone. It means that even if you think you’re friends with people you work with, when it comes to difficult decisions, the main priority is always the business. This means that even if your friendship is important to you, it might not be the most important thing to consider when making business decisions.