My favorite fruit is grapes. Because with grapes, you always get another chance. 'Cause, you know, if you have a crappy apple or a peach, you're stuck with that crappy piece of fruit. But if you have a crappy grape, no problem - just move on to the next. 'Grapes: The Fruit of Hope.'

This quote is saying that the speaker’s favorite fruit is grapes because if one grape is not good, they can just choose another. Grapes are seen as having the potential to give new chances, so the quote calls them “The Fruit of Hope” – meaning that grapes bring hope of having a good snack each time.