No one wants to die. Even people who want to go to heaven don't want to die to get there. And yet death is the destination we all share. No one has ever escaped it. And that is as it should be, because Death is very likely the single best invention of Life. It is Life's change agent. It clears out the old to make way for the new.

This quote is saying that death is inevitable. No matter how much people may not want to die, it is something that we all have to experience. Even though death is sad and difficult, it is actually a useful and necessary part of life. Death helps to bring about change because it makes room for new people, ideas, and experiences. Without death, life would lack progress and growth.