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This quote is referring to the joy of studying and the peace and quiet that can be found while reading books. The “love of learning” is the excitement and enthusiasm of pursuing knowledge and understanding. The “sequestered nooks” are quiet and peaceful locations, such as a library or study, where books can be read and enjoyed. The “sweet serenity of books” is the calm and soothing feeling that reading can bring. When people find these comfortable locations and immerse themselves in books, they can find a sense of peace and relaxation.