We want 'Doll & Em' to be something we're proud of. We'd love to do another series, but it's not the be-all and end-all. Our friendship is the be-all and end-all.

This quote means that the goal of the show “Doll & Em” is to make something that the creators feel proud of, but their friendship is more important to them than the success of the show. They would like to do another series, but it is not the most important thing to them. Their friendship is the most important thing.