You can't connect the dots looking forward; you can only connect them looking backwards. So you have to trust that the dots will somehow connect in your future. You have to trust in something - your gut, destiny, life, karma, whatever. This approach has never let me down, and it has made all the difference in my life.

This quote is saying that you cannot plan for the future, because it is impossible to predict what will happen. You can only look at past events and experiences to understand what is in store for you in the future. Therefore, you need to put your trust in a power greater than yourself- like your gut instincts, fate, or a spiritual force- that will keep you safe and guide you towards success. The speaker has found this approach to be reliable and it has had positive results in his life.